News for Healthier Living

Summit Supercomputer Draws Molecular Blueprint for Repairing Damaged DNA

Researchers at Georgia State University used the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision repair, or NER. They built a computer model of a critical NER component called the pre-incision complex, or PInC, which plays a key role in regulating DNA repair processes in the latter stages of the NER pathway. Decoding NER's sophisticated sequence of events and the role of PInC in the pathway could provide key insights into developing novel treatments and preventing conditions that lead to premature aging and certain types of cancer.

March 12, 2025


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